GHRP-6
Growth Hormone Releasing Peptide-6
Overview
GHRP-6 is a synthetic hexapeptide that stimulates natural growth hormone release from the pituitary gland. It is known for its strong appetite-stimulating effects via ghrelin receptor activation, making it useful for individuals seeking to increase caloric intake alongside muscle growth.
Mechanism of Action
GHRP-6 acts as a ghrelin mimetic, binding to GHS-R1a receptors on pituitary somatotrophs. It stimulates GH release via a different mechanism than GHRH, creating additive effects when combined. It also suppresses somatostatin, further amplifying GH release. Its ghrelin activity strongly stimulates appetite.
Dosage Information
Typical Dose
100-300 mcg
Frequency
2-3 times daily
Administration
Subcutaneous injection
Notes
Administer on empty stomach. Strong appetite increase typically occurs 20-30 minutes post-injection. Can be combined with GHRH analogs for enhanced GH release.
Potential Side Effects
Research References
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Stacking Compatibility
Quick Facts
- Administration
- Subcutaneous injection
- Typical Dose
- 100-300 mcg
- Frequency
- 2-3 times daily
- References
- 2 studies