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CJC-1295

CJC-1295 with Drug Affinity Complex (DAC)

Overview

CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates pituitary growth hormone release. The DAC modification extends its half-life to approximately 6-8 days, allowing for less frequent dosing. It is widely used for anti-aging, fat loss, sleep improvement, and overall growth hormone optimization.

Mechanism of Action

CJC-1295 binds to GHRH receptors on the anterior pituitary, stimulating the synthesis and secretion of growth hormone (GH) in a pulsatile manner. The DAC linker binds to albumin in the bloodstream, dramatically extending the half-life. This results in sustained GH elevation without the supraphysiological spikes associated with exogenous GH administration.

Dosage Information

Typical Dose

1-2 mg per week

Frequency

1-2 times per week

Administration

Subcutaneous injection

Notes

Best results when combined with a GHRP such as Ipamorelin. Administer before bed to synergize with natural GH release during sleep. Cycle 8-12 weeks on, 4 weeks off.