AOD-9604
Advanced Obesity Drug 9604
Overview
AOD-9604 is a modified fragment (amino acids 177-191) of the human growth hormone polypeptide with an added tyrosine at the N-terminus. It retains the fat-metabolizing properties of GH without its growth-promoting or diabetogenic effects, making it a targeted fat loss peptide.
Mechanism of Action
AOD-9604 stimulates lipolysis (fat breakdown) and inhibits lipogenesis (fat formation) by mimicking the way natural growth hormone regulates fat metabolism. It activates beta-3 adrenergic receptors in adipose tissue. Importantly, it does not affect IGF-1 levels or insulin sensitivity, distinguishing it from full-length GH. Recent research also shows chondroprotective properties.
Dosage Information
Typical Dose
300 mcg
Frequency
Once daily
Administration
Subcutaneous injection
Notes
Best administered in the morning on an empty stomach. Do not eat for 15-20 minutes after injection. Cycle 12 weeks on, 4 weeks off. Has GRAS (Generally Recognized as Safe) status from FDA for oral use.
Potential Side Effects
Research References
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Quick Facts
- Administration
- Subcutaneous injection
- Typical Dose
- 300 mcg
- Frequency
- Once daily
- References
- 2 studies