Ipamorelin
Ipamorelin Acetate
Overview
Ipamorelin is one of the most selective growth hormone secretagogues available. Unlike other GH-releasing peptides, it stimulates GH release without significantly affecting cortisol, prolactin, or appetite. This selectivity makes it one of the safest and most popular peptides for anti-aging and body composition improvement.
Mechanism of Action
Ipamorelin selectively binds to the ghrelin/growth hormone secretagogue receptor (GHS-R) in the pituitary gland, triggering a dose-dependent release of growth hormone. Unlike GHRP-6 or GHRP-2, it does not significantly stimulate ACTH, cortisol, or prolactin release, making it highly selective for GH secretion only.
Dosage Information
Typical Dose
200-300 mcg
Frequency
2-3 times daily
Administration
Subcutaneous injection
Notes
Best administered on an empty stomach (at least 2 hours after eating). Pre-bed dosing is popular to enhance natural GH pulse during sleep. Often stacked with CJC-1295 for synergistic effect.
Potential Side Effects
Research References
Community Experiences
No experiences shared yet. Be the first!
Stacking Compatibility
In These Stacks
Quick Facts
- Administration
- Subcutaneous injection
- Typical Dose
- 200-300 mcg
- Frequency
- 2-3 times daily
- References
- 2 studies