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TB-500

Thymosin Beta-4

Overview

TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring 43-amino-acid peptide present in virtually all human and animal cells. It plays a critical role in tissue repair, wound healing, and the regulation of actin in cell building. TB-500 is known for its systemic distribution and ability to promote healing throughout the body.

Mechanism of Action

TB-500 upregulates actin and promotes cell migration, blood vessel formation (angiogenesis), and wound healing. It reduces inflammation by downregulating pro-inflammatory cytokines while supporting the formation of new blood vessels and tissue. It also promotes stem cell maturation and differentiation, and has cardioprotective properties.

Dosage Information

Typical Dose

2-5 mg

Frequency

2 times per week (loading), 2 times per month (maintenance)

Administration

Subcutaneous injection

Notes

Loading phase of 4-6 weeks at higher dose, then transition to maintenance dosing. Systemic effects mean injection location is less critical than with BPC-157.

Potential Side Effects

Head rush (temporary)Injection site irritationFatigue (uncommon)Mild nausea

Research References

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Stacking Compatibility

Quick Facts

Administration
Subcutaneous injection
Typical Dose
2-5 mg
Frequency
2 times per week (loading), 2 times per month (maintenance)
References
3 studies