Mitochondrial Optimization
Maximum mitochondrial function and cellular energy production
About This Stack
The most advanced cellular energy stack targeting mitochondrial function from multiple angles: MOTS-c for metabolic regulation, SS-31 for electron transport chain repair, Humanin for mitochondrial-mediated cytoprotection, and NAD+ for coenzyme restoration. Addresses the energy factory of every cell.
Synergy Explanation
MOTS-c activates AMPK for metabolic optimization and communicates mitochondrial signals to the nucleus. SS-31 stabilizes cardiolipin in the inner mitochondrial membrane, restoring electron transport chain efficiency. Humanin provides anti-apoptotic protection, preventing mitochondrial-triggered cell death. NAD+ replenishes the critical coenzyme needed for oxidative phosphorylation and sirtuin function.
Included Peptides
MOTS-c
5-10 mg · 3 times per week · Subcutaneous injection
SS-31 (Elamipretide)
40 mg daily · Once daily (clinical trials) · Subcutaneous injection
Humanin
Research dosing varies · Varies · Subcutaneous injection
NAD+
100-500 mg · Varies by route · Intravenous, subcutaneous, or oral (as precursors NMN/NR)
Precautions
- Most advanced stack — requires thorough understanding of each compound
- SS-31 and Humanin have limited human clinical data
- Multiple injections required on different schedules
- Very expensive to run simultaneously
- Regular metabolic bloodwork recommended
- Consult a longevity medicine specialist