Research Overview
All peptides organized by evidence level — from well-established clinical compounds to early-stage preclinical research. Includes human trials, animal studies, in vitro data, and systematic reviews.
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Well-evidenced
(9)Evidence score 75–100
Thymosin Alpha 1
Thymalfasin (Thymosin Alpha 1)
Thymosin Alpha 1 is a 28-amino acid peptide naturally produced by the thymus gland that plays a critical role in immune system maturation and regulati...
Oxytocin
Oxytocin
Oxytocin is a nine-amino acid neuropeptide hormone produced in the hypothalamus. Often called the "love hormone" or "bonding hormone," it plays crucia...
Melanotan I
Afamelanotide
Melanotan I (Afamelanotide) is a synthetic alpha-melanocyte-stimulating hormone (alpha-MSH) analog approved in Europe and Australia under the brand na...
PT-141
Bremelanotide
PT-141 (Bremelanotide) is a melanocortin receptor agonist originally developed from Melanotan II research. Unlike PDE5 inhibitors that work on blood f...
GLP-1
Glucagon-like Peptide-1
Glucagon-like Peptide-1 (GLP-1) is an endogenous incretin hormone secreted by L-cells in the small intestine in response to food intake. It plays a ce...
Pentosan Polysulfate
Pentosan Polysulfate Sodium (PPS)
Pentosan Polysulfate is a semi-synthetic polysulfated xylan derived from beechwood hemicellulose. It is FDA-approved (brand name Elmiron) for intersti...
IGF-1
Insulin-like Growth Factor 1
Insulin-like Growth Factor 1 (IGF-1) is a naturally occurring 70-amino-acid peptide hormone produced primarily in the liver in response to growth horm...
Semaglutide
Semaglutide
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist originally developed for type 2 diabetes management and approved by the FDA under th...
LL-37
LL-37 (Human Cathelicidin)
LL-37 is the only cathelicidin antimicrobial peptide found in humans. It is a 37-amino acid peptide that serves as a critical component of the innate...
Established
(13)Evidence score 55–75
Resveratrol
trans-Resveratrol
Resveratrol is a polyphenolic stilbene compound found in red wine, grapes, and certain berries that has been extensively studied for its potential lon...
Liraglutide
Liraglutide
Liraglutide is a GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Victoza) and obesity management (Saxenda). It was the first GLP-1 ana...
DSIP
Delta Sleep Inducing Peptide
DSIP is a neuropeptide first identified in 1977 from the blood of rabbits in an induced state of sleep. It is involved in sleep regulation, particular...
Rapamycin
Sirolimus
Rapamycin (Sirolimus) is a macrolide compound originally discovered in soil bacteria from Easter Island (Rapa Nui) that functions as a potent mTOR inh...
VIP
Vasoactive Intestinal Peptide
Vasoactive Intestinal Peptide (VIP) is a 28-amino-acid neuropeptide found throughout the central and peripheral nervous system gastrointestinal tract...
Fisetin
3,3',4',7-tetrahydroxyflavone
Fisetin is a flavonoid polyphenol found in strawberries, apples, and other fruits that has emerged as one of the most potent senolytic compounds ident...
Selank
Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
Selank is a synthetic heptapeptide analog of the naturally occurring immunomodulatory peptide tuftsin. Developed at the Institute of Molecular Genetic...
Alpha-MSH
Alpha-Melanocyte-Stimulating Hormone
Alpha-MSH is a 13-amino-acid endogenous peptide produced from proopiomelanocortin (POMC) in the pituitary gland skin and brain. It is the natural liga...
NAD+
Nicotinamide Adenine Dinucleotide
NAD+ is a critical coenzyme found in every cell of the body, essential for hundreds of metabolic processes including energy production, DNA repair, ge...
GDF-11
Growth Differentiation Factor 11
GDF-11 (Growth Differentiation Factor 11) is a TGF-beta superfamily member that generated enormous scientific excitement following 2013-2014 research...
TB-500
Thymosin Beta-4
TB-500 is a synthetic version of Thymosin Beta-4, a naturally occurring 43-amino-acid peptide present in virtually all human and animal cells. It play...
Tirzepatide
Tirzepatide
Tirzepatide is a first-in-class dual GIP/GLP-1 receptor agonist approved by the FDA under the brand name Mounjaro for type 2 diabetes and Zepbound for...
GHRP-2
Growth Hormone Releasing Peptide-2
GHRP-2 is considered one of the most potent growth hormone releasing peptides available. It stimulates GH release more effectively than GHRP-6 with le...
Emerging
(5)Evidence score 35–55
Kisspeptin
Kisspeptin-10 (Metastin 45-54)
Kisspeptin is a peptide encoded by the KISS1 gene that plays a master regulatory role in the hypothalamic-pituitary-gonadal (HPG) axis. It is the prim...
Humanin
Humanin (HN)
Humanin is a 24-amino acid mitochondrial-derived peptide first discovered in 2001 in surviving neurons of Alzheimer's disease patients. It is the foun...
SS-31 (Elamipretide)
Elamipretide (D-Arg-2'6'-dimethylTyr-Lys-Phe-NH2)
SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that selectively concentrates in the inner mitochondrial membrane. It stabilizes cardioli...
GHK-Cu
Copper Peptide GHK-Cu (Glycyl-L-Histidyl-L-Lysine)
GHK-Cu is a naturally occurring copper-binding tripeptide found in human plasma, saliva, and urine. Levels decline significantly with age. It is one o...
FOXO4-DRI
FOXO4-D-Retro-Inverso Peptide
FOXO4-DRI is a synthetic D-amino acid retro-inverso peptide designed to selectively eliminate senescent cells by interfering with the interaction betw...
Preclinical
(17)Evidence score 15–35
GHRP-6
Growth Hormone Releasing Peptide-6
GHRP-6 is a synthetic hexapeptide that stimulates natural growth hormone release from the pituitary gland. It is known for its strong appetite-stimula...
NSI-189
NSI-189 Phosphate
NSI-189 is a synthetic aminopyridine-benzylpiperazine compound originally developed by Neuralstem Inc that has demonstrated neurogenic properties in t...
Epithalon
Epitalon (Ala-Glu-Asp-Gly)
Epithalon is a synthetic tetrapeptide based on Epithalamin, the natural peptide produced by the pineal gland. Developed by Professor Vladimir Khavinso...
Tesamorelin
Tesamorelin Acetate
Tesamorelin is a synthetic GHRH analog that is FDA-approved for the treatment of HIV-associated lipodystrophy. It is the only GHRH peptide with full F...
Sermorelin
Sermorelin Acetate (GRF 1-29 NH2)
Sermorelin is a truncated analog of natural GHRH containing the first 29 amino acids, which is the minimum fragment needed for full biological activit...
SNAP-8
Acetyl Octapeptide-3
SNAP-8 is a synthetic octapeptide that mimics the N-terminal end of SNAP-25, a component of the SNARE complex involved in neuromuscular signaling. It...
Thymulin
Facteur Thymique Serique (FTS)
Thymulin is a nonapeptide hormone produced exclusively by thymic epithelial cells that plays a central role in T-lymphocyte maturation and immune func...
Cerebrolysin
Cerebrolysin (Porcine Brain-Derived Peptide Preparation)
Cerebrolysin is a multi-modal neuropeptide preparation derived from purified porcine brain proteins. It contains a mixture of low-molecular-weight neu...
TA-1
Thymosin Alpha-1 Fragment
TA-1 refers to short active fragments of Thymosin Alpha-1 that retain immunomodulatory activity with potentially improved pharmacokinetics. While full...
IGF-1 LR3
Insulin-like Growth Factor 1 Long R3
IGF-1 LR3 is a modified version of IGF-1 with 83 amino acids (vs. 70 in native IGF-1) and an arginine substitution at position 3. These modifications...
Klotho
Alpha-Klotho Protein Fragment
Klotho is a longevity-associated protein named after the Greek goddess who spins the thread of life. Mice lacking the klotho gene show dramatic premat...
MGF
Mechano Growth Factor (IGF-1Ec)
MGF is a splice variant of IGF-1 that is expressed locally in damaged muscle tissue following mechanical stimulation (exercise or injury). It activate...
GHK-Cu
Glycyl-L-Histidyl-L-Lysine Copper Complex
GHK-Cu (Glycyl-L-Histidyl-L-Lysine) is a naturally occurring copper-binding tripeptide found in human plasma saliva and urine that declines significan...
Collagen Peptides
Hydrolyzed Collagen (Type I, II, III)
Collagen peptides are short chain amino acid sequences derived from hydrolyzed collagen protein the most abundant structural protein in the human body...
Semax
Semax (Met-Glu-His-Phe-Pro-Gly-Pro)
Semax is a synthetic peptide analog of ACTH(4-10), a fragment of adrenocorticotropic hormone. Developed at the Institute of Molecular Genetics of the...
KPV
KPV Tripeptide (Lys-Pro-Val)
KPV is a naturally occurring anti-inflammatory tripeptide derived from the C-terminal end of alpha-melanocyte stimulating hormone (α-MSH). It retains...
Melanotan II
Melanotan II Acetate
Melanotan II is a synthetic cyclic peptide analog of alpha-melanocyte stimulating hormone (α-MSH). It activates melanocortin receptors, producing effe...
No data
(26)Evidence score 0–15
Follistatin 344
Follistatin 344
Follistatin 344 is a naturally occurring glycoprotein that acts as an antagonist to myostatin, the protein that limits muscle growth. By neutralizing...
MOTS-c
Mitochondrial Open Reading Frame of the 12S rRNA Type-c
MOTS-c is a mitochondrial-derived peptide (MDP) encoded within the mitochondrial genome. Discovered in 2015 by researchers at USC, it functions as a m...
Pinealon
EDR Tripeptide (Glu-Asp-Arg)
Pinealon is a synthetic tripeptide (Glu-Asp-Arg) developed at the St. Petersburg Institute of Bioregulation and Gerontology in Russia. It is a bioregu...
BPC-157
Body Protection Compound-157 (Gastric Pentadecapeptide)
BPC-157 is a synthetic pentadecapeptide derived from a protective protein found in human gastric juice. It has demonstrated remarkable healing propert...
Dihexa
N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Dihexa is a small peptide-derived compound developed at Washington State University that acts as a potent hepatocyte growth factor (HGF) agonist. It h...
HGH Fragment 176-191
Human Growth Hormone Fragment 176-191
HGH Fragment 176-191 is the specific portion of the growth hormone molecule responsible for its fat-burning activity. This small peptide fragment repr...
Ipamorelin
Ipamorelin Acetate
Ipamorelin is one of the most selective growth hormone secretagogues available. Unlike other GH-releasing peptides, it stimulates GH release without s...
Thymosin Beta-4 Sulfoxide
Thymosin Beta-4 Sulfoxide
Thymosin Beta-4 Sulfoxide is the naturally oxidized form of Thymosin Beta-4 (TB-500) in which the methionine residue at position 6 is converted to met...
Wolverine Peptide Blend
BPC-157 + TB-500 Combination
The "Wolverine" blend is a popular combination concept pairing BPC-157 and TB-500, named for the fictional character's extraordinary healing abilities...
CJC-1295
CJC-1295 with Drug Affinity Complex (DAC)
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates pituitary growth hormone release. The DAC modification exten...
AOD-9604
Advanced Obesity Drug 9604
AOD-9604 is a modified fragment (amino acids 177-191) of the human growth hormone polypeptide with an added tyrosine at the N-terminus. It retains the...
PT-141
Bremelanotide
PT-141 (Bremelanotide) is a melanocortin receptor agonist originally developed from Melanotan II research and FDA-approved in 2019 under the brand nam...
BPC-157 + TB-500
Body Protection Compound-157 + Thymosin Beta-4
The combination of BPC-157 and TB-500 represents one of the most widely used peptide stacking protocols in the recovery and athletic performance commu...
Cortagen
Ala-Glu-Asp-Pro (AEDP)
Cortagen is a synthetic tetrapeptide bioregulator developed at the St. Petersburg Institute of Bioregulation and Gerontology targeting brain tissue an...
P21
P21 (CNTF-derived peptide)
P21 is a synthetic peptide derived from the ciliary neurotrophic factor (CNTF) binding interface that has demonstrated potent neurogenic and cognitive...
Anastrozole
Anastrozole
Anastrozole is a third-generation non-steroidal aromatase inhibitor FDA-approved for breast cancer treatment. In the hormonal health community it is w...
Enclomiphene
Enclomiphene Citrate
Enclomiphene is the trans-isomer of clomiphene citrate, a selective estrogen receptor modulator (SERM) used to stimulate endogenous testosterone produ...
Melatonin
N-acetyl-5-methoxytryptamine
Melatonin is a naturally occurring hormone produced by the pineal gland that regulates circadian rhythm and the sleep-wake cycle. It is also a potent...
Gonadorelin
Gonadotropin-Releasing Hormone
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), the hypothalamic peptide that triggers the release of FSH and LH from the pi...
HCG
Human Chorionic Gonadotropin
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone produced during pregnancy that mimics luteinizing hormone (LH) and stimulates testosteron...
Testosterone
Testosterone
Testosterone is the primary male sex hormone and an anabolic steroid naturally produced in the testes in men and in smaller amounts in the ovaries and...
Metformin
Metformin Hydrochloride
Metformin is a biguanide compound derived from French lilac (Galega officinalis) that has been used clinically for type 2 diabetes since 1957. It is t...
Berberine
Berberine Hydrochloride
Berberine is an isoquinoline alkaloid found in several plants including barberry, goldenseal, and Oregon grape that has been used in traditional Chine...
Spermidine
Spermidine
Spermidine is a naturally occurring polyamine found in all living cells and in many foods including wheat germ, soybeans, aged cheese, and mushrooms....
Quercetin
Quercetin
Quercetin is one of the most abundant dietary flavonoids, found in onions, apples, capers, and many other plant foods. It is one of the first senolyti...
NMN
Nicotinamide Mononucleotide
Nicotinamide Mononucleotide (NMN) is a nucleotide naturally occurring in all living cells and a direct precursor to NAD+ — the essential coenzyme invo...